细胞生物学研究中的激活剂和抑制剂

发布时间 : 星期二 文章细胞生物学研究中的激活剂和抑制剂更新完毕开始阅读

CRM1-mediated nuclear export. Mol Biol Cell. 2005;16:2999-3009 PMID 15814838

Meissner T, Krause E, Vinkemeier U. Ratjadone and leptomycin B block CRM1-dependent nuclear export by identical mechanisms. FEBS Lett. 2004;576:27-30 PMID 15474004

K?ster M, Lykke-Andersen S, Elnakady Y, Gerth K, Washausen P, Hofle G, et al. Ratjadones inhibit nuclear export by blocking CRM1/exportin 1. Exp Cell Res. 2003;286:321-31 PMID 12749860

Adelsberger H, Lepier A, Dudel J. Activation of rat recombinant alpha(1)beta(2)gamma(2S) GABA(A) receptor by the insecticide ivermectin. Eur J Pharmacol. 2000;394:163-70 PMID 10771281 Wagstaff K, Rawlinson S, Hearps A, Jans D. An AlphaScreen?-based assay for high-throughput screening for specific inhibitors of nuclear import. J Biomol Screen. 2011;16:192-200 PMID 21297106

CrossRef

Wagstaff K, Sivakumaran H, Heaton S, Harrich D, Jans D. Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus. Biochem J. 2012;443:851-6 PMID 22417684 CrossRef

Levin A, Hayouka Z, Friedler A, Loyter A. Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells. Nucleus. 2010;1:422-31 PMID 21326825 CrossRef Webb R. Smooth muscle contraction and relaxation. Adv Physiol Educ. 2003;27:201-6 PMID 14627618 Tamaoki T, Nomoto H, Takahashi I, Kato Y, Morimoto M, Tomita F. Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase. Biochem Biophys Res Commun. 1986;135:397-402 PMID

3457562

Jin M, Ande A, Kumar A, Kumar S. Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway. Cell Death Dis. 2013;4:e554 PMID 23519123 CrossRef Ward N, O'Brian C. Kinetic analysis of protein kinase C inhibition by staurosporine: evidence that inhibition entails inhibitor binding at a conserved region of the catalytic domain but not competition with substrates. Mol Pharmacol. 1992;41:387-92 PMID 1538715

Koyanagi M, Takahashi J, Arakawa Y, Doi D, Fukuda H, Hayashi H, et al. Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors. J Neurosci Res. 2008;86:270-80 PMID 17828770

Watanabe K, Ueno M, Kamiya D, Nishiyama A, Matsumura M, Wataya T, et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat Biotechnol. 2007;25:681-6 PMID 17529971 Nobes C, Hall A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol. 1999;144:1235-44 PMID 10087266

Yu Z, Liu M, Fu P, Xie M, Wang W, Luo X. ROCK inhibition with Y27632 promotes the proliferation and

cell cycle progression of cultured astrocyte from spinal cord. Neurochem Int. 2012;61:1114-20 PMID

22929997 CrossRef

Hudson C, Heesom K, Lopez Bernal A. Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1). Mol Hum Reprod. 2012;18:265-79 PMID 22155728 CrossRef

Wang T, Kendig D, Trappanese D, Smolock E, Moreland R. Phorbol 12,13-dibutyrate-induced, protein kinase C-mediated contraction of rabbit bladder smooth muscle. Front Pharmacol. 2012;2:83 PMID

22232602

Fuentes E, Leemhuis J, Stark G, Lang E. Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells. J Brachial Plex Peripher Nerve Inj. 2008;3:19 PMID

18817543 CrossRef

Hammar E, Tomas A, Bosco D, Halban P. Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function. Endocrinology. 2009;150:2072-9 PMID 19106222

CrossRef

Makishima M, Honma Y, Hozumi M, Sampi K, Hattori M, Motoyoshi K. Induction of differentiation of human leukemia cells by inhibitors of myosin light chain kinase. FEBS Lett. 1991;287:175-7 PMID 1879528 Yamamoto-Yamaguchi Y, Makishima M, Kanatani Y, Kasukabe T, Honma Y. Reversible differentiation of human monoblastic leukemia U937 cells by ML-9, an inhibitor of myosin light chain kinase. Exp Hematol. 1996;24:682-9 PMID 8635523

Ito S, Kume H, Honjo H, Kodama I, Katoh H, Hayashi H, et al. ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealis. Eur J Pharmacol. 2004;486:325-33

PMID 14985055

Saitoh M, Ishikawa T, Matsushima S, Naka M, Hidaka H. Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. J Biol Chem. 1987;262:7796-801 PMID 3108259

Lin H, Cadete V, Sawicka J, Wozniak M, Sawicki G. Effect of the myosin light chain kinase inhibitor ML-7 on the proteome of hearts subjected to ischemia-reperfusion injury. J Proteomics. 2012;75:5386-95 PMID

22749930 CrossRef

Nakanishi S, Yamada K, Kase H, Nakamura S, Nonomura Y. K-252a, a novel microbial product, inhibits smooth muscle myosin light chain kinase. J Biol Chem. 1988;263:6215-9 PMID 2966151

Hashimoto Y, Nakayama T, Teramoto T, Kato H, Watanabe T, Kinoshita M, et al. Potent and preferential inhibition of Ca2+/calmodulin-dependent protein kinase II by K252a and its derivative, KT5926. Biochem Biophys Res Commun. 1991;181:423-9 PMID 1659814

Kase H, Iwahashi K, Nakanishi S, Matsuda Y, Yamada K, Takahashi M, et al. K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem

Biophys Res Commun. 1987;142:436-40 PMID 3028414

Chin L, Murray S, Doherty P, Singh S. K252a induces cell cycle arrest and apoptosis by inhibiting Cdc2 and Cdc25c. Cancer Invest. 1999;17:391-5 PMID 10434949

Minardi A, Christ D, Saz H. Effects of calmodulin and protein kinase C antagonists on muscle in the filariid, Acanthocheilonema viteae. J Parasitol. 1995;81:989-96 PMID 8544077

Pinto C, Reif G, Nivens E, White C, Wallace D. Calmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl- secretion by human autosomal dominant polycystic kidney cells. Am J Physiol Renal Physiol. 2012;303:F1412-24 PMID 22952279 CrossRef Hidaka H, Sasaki Y, Tanaka T, Endo T, Ohno S, Fujii Y, et al.

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc Natl Acad Sci U S A. 1981;78:4354-7 PMID 6945588

Song Y, Lin P, Chen M. The effects of calcium channel blocker benidipine and calmodulin antagonist W7 on GDP-binding capacity of brown adipose tissue in mice. Biol Trace Elem Res. 2009;127:245-50 PMID

18953505 CrossRef

Kodama M, Yamamoto H, Kanaide H. Myosin phosphorylation and Ca2+ sensitization in porcine coronary arterial smooth muscle stimulated with endothelin-1. Eur J Pharmacol. 1994;288:69-77 PMID

7705470

Abe Y, Kasuya Y, Kudo M, Yamashita K, Goto K, Masaki T, et al. Endothelin-1-induced phosphorylation of the 20-kDa myosin light chain and caldesmon in porcine coronary artery smooth muscle. Jpn J Pharmacol. 1991;57:431-5 PMID 1813669

Masamune A, Satoh M, Kikuta K, Suzuki N, Shimosegawa T. Endothelin-1 stimulates contraction and migration of rat pancreatic stellate cells. World J Gastroenterol. 2005;11:6144-51 PMID 16273641 Weigand L, Sylvester J, Shimoda L. Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol. 2006;290:L284-90 PMID

16155085

Schoenwaelder S, Burridge K. Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho. A novel role for the calpain inhibitor calpeptin in the inhibition of protein-tyrosine phosphatases. J Biol Chem. 1999;274:14359-67 PMID 10318859

Kang Y, Shin H. Vasorelaxant effect of Cinnamomi ramulus ethanol extract via rho-kinase signaling pathway. Am J Chin Med. 2011;39:867-78 PMID 21905278 CrossRef

Minshall R, Vandenbroucke E, Holinstat M, Place A, Tiruppathi C, Vogel S, et al. Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvasc Res. 2010;80:240-9 PMID 20417648 CrossRef

Ruiz-Loredo A, Lopez E, López-Colomé A. Thrombin stimulates stress fiber assembly in RPE cells by PKC/CPI-17-mediated MLCP inactivation. Exp Eye Res. 2012;96:13-23 PMID 22300615 CrossRef Park S, Rasmussen H. Activation of tracheal smooth muscle contraction: synergism between Ca2+ and activators of protein kinase C. Proc Natl Acad Sci U S A. 1985;82:8835-9 PMID 2417230

Staudt M, Depass A, Sarkar D, Fisher P. Model cell culture system for defining the molecular and biochemical events mediating terminal differentiation of human melanoma cells. J Cell Physiol. 2009;218:304-14 PMID 18844238 CrossRef

Bogi K, Lorenzo P, Acs P, Szallasi Z, Wagner G, Blumberg P. Comparison of the roles of the C1a and C1b domains of protein kinase C alpha in ligand induced translocation in NIH 3T3 cells. FEBS Lett. 1999;456:27-30 PMID 10452523

Bossu J, Elhamdani A, Feltz A, Tanzi F, Aunis D, Thierse D. Voltage-gated Ca entry in isolated bovine capillary endothelial cells: evidence of a new type of BAY K 8644-sensitive channel. Pflugers Arch. 1992;420:200-7 PMID 1377815

Benaim G, Garcia-Marchan Y, Reyes C, Uzcanga G, Figarella K. Identification of a sphingosine-sensitive Ca2+ channel in the plasma membrane of Leishmania mexicana. Biochem Biophys Res Commun. 2013;430:1091-6 PMID 23261440 CrossRef

Noh A, Park H, Zheng T, Ha H, Yim M. L-type Ca(2+) channel agonist inhibits RANKL-induced osteoclast formation via NFATc1 down-regulation. Life Sci. 2011;89:159-64 PMID 21683712 CrossRef Mukherjee S, Trice J, Shinde P, Willis R, Pressley T, Perez-Zoghbi J. Ca2+ oscillations, Ca2+ sensitization, and contraction activated by protein kinase C in small airway smooth muscle. J Gen Physiol. 2013;141:165-78 PMID 23359281 CrossRef

Verhovshek T, Cai Y, Osborne M, Sengelaub D. Androgen regulates brain-derived neurotrophic factor in spinal motoneurons and their target musculature. Endocrinology. 2010;151:253-61 PMID 19880806

CrossRef

Schmidt A, Koch P. Desmosomes: just cell adhesion or is there more?. Cell Adh Migr. 2007;1:28-32 PMID

19262094

Green K, Jones J. Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J. 1996;10:871-81 PMID 8666164

Takada Y, Ye X, Simon S. The integrins. Genome Biol. 2007;8:215 PMID 17543136

Berman A, Kozlova N, Morozevich G. Integrins: structure and signaling. Biochemistry (Mosc). 2003;68:1284-99 PMID 14756624

Humphries J, Byron A, Humphries M. Integrin ligands at a glance. J Cell Sci. 2006;119:3901-3 PMID

16988024

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